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37 search results for: synthetic

21

CRISPR/Cas Armed with Enzyme That Controls Translation

CRISPR/Cas systems are best known as “gene scissors” for correcting genetic defects. Precise targeting of specific regions in DNA of plants, animals, and microorganisms is the reason CRISPR recently became a favorite tool of many researchers. Now, a group from the University of Freiburg identified an enzyme which assists the CRISPR/Cas system in correctly regulating […]

23

Breakthroughs in 2017 That Caught Our Attention

The pace of progress in science in recent years is remarkable. Mostly, due to the fact that processes which took weeks to complete can now be done in minutes. Therefore, the past year was definitely fruitful for science. Scientists cooperated and even some global scale projects saw the light of day. Splice would like to review the […]

26

Scientists Successfully Folded a Protein Within a Protein

A research group from Singapore has developed a bacterial protein nanoparticle shell which folds and protects recombinant proteins within it. A fundamental breakthrough in the rapidly expanding field of synthetic biology, this technology can improve yields of proteins with biological activity by 100-fold and shield recombinant proteins from heat, harsh chemicals and proteolysis.

28

Big Step Forward for Protein Engineering

A group of US and Canadian researchers conducted the largest-scale testing of folding stability for computationally designed proteins. More than 15,000 newly designed small proteins were tested for correlation between folding and function which resulted in significant protein modeling improvements.