CRISPR/Cas systems are best known as “gene scissors” for correcting genetic defects. Precise targeting of specific regions in DNA of plants, animals, and microorganisms is the reason CRISPR recently became a favorite tool of many researchers. Now, a group from the University of Freiburg identified an enzyme which assists the CRISPR/Cas system in correctly regulating […]
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For the second year in a row, life expectancy in the United States declined due to an opioid crisis. Scientists have high hopes for a new opioid vaccine developed by the US military, that shows promising results in mice and rats.
The pace of progress in science in recent years is remarkable. Mostly, due to the fact that processes which took weeks to complete can now be done in minutes. Therefore, the past year was definitely fruitful for science. Scientists cooperated and even some global scale projects saw the light of day. Splice would like to review the […]
Scientists managed to add X and Y nucleotide bases to Escherichia coli bacteria’s natural genetic alphabet and create entirely new, synthetic proteins. This is a major step toward creating artificial life but the goal of their study was actually to develop a novel protein-based drug treatments.
Slowing, stopping, or even reversing aging has always been an ongoing topic in science. Now, scientists used the synthetic compound resveratrol, found naturally in chocolate and other consumables, to turn back the biological clock in senescent cells, causing them to start dividing again.
A research group from Singapore has developed a bacterial protein nanoparticle shell which folds and protects recombinant proteins within it. A fundamental breakthrough in the rapidly expanding field of synthetic biology, this technology can improve yields of proteins with biological activity by 100-fold and shield recombinant proteins from heat, harsh chemicals and proteolysis.
Researchers developed a new approach to cell therapy that uses nanoparticles to deliver genetic material that induces changes in the cell´s transient gene expression. An approach that is faster and cheaper to develop, more customizable and as simple as ‘just add water’.
A group of US and Canadian researchers conducted the largest-scale testing of folding stability for computationally designed proteins. More than 15,000 newly designed small proteins were tested for correlation between folding and function which resulted in significant protein modeling improvements.
The study of algae, more recently called Phycology, has always intrigued human curiosity. The Ancient Egyptians used algae for cosmetic alchemy and we have discovered a host of uses for this versatile photosynthetic organism since the 19th century.
US scientists discovered a surprising hidden function of mammalian lungs – they help produce blood. Their study on mice showed that more than half of all platelets in mice are produced by the lungs, a process long attributed to bone marrow.
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